Zoom Out For Sharper Web Images
This is a tip we use almost daily when we have to greatly reduce the size and/or resolution of an image. Sometimes when you make a drastic size/resolution change, it can really make the resulting image blurry, so what we do is simply zoom out on the image so that the window and image are at either 50% or 25% view. Then, we take a screen capture of our image window at the new smaller size. That way, the image still looks sharp, but it's much smaller when we open the screen capture in Photoshop. The trick to making this work is using either a 50%, 25%, or 12.5% view size for making the capture. If you view the image at 66.7%, 33.3%, or 16.7%, the image won't be as crisp (because of the way Photoshop draws the image at those views).